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Volume 20, Number 5, 2015

Effect of radiotherapy delay in overall treatment time on local control and survival in head and neck cancer: Review of the literature

José A. González Ferreira, Javier Jaén Olasolo, Ignacio Azinovic, Branislav Jeremic


Treatment delays in completing radiotherapy (RT) for many neoplasms are a major problem affecting treatment outcome, as increasingly shown in the literature. Overall treatment time (OTT) could be a critical predictor of local tumor control and/or survival. In an attempt to establish a protocol for managing delays during RT, especially for heavily overloaded units, we have extensively reviewed the available literature on head and neck cancer. We confirmed a large deleterious effect of prolonged OTT on both local control and survival of these patients.

Signature: Rep Pract Oncol Radiother, 2015; 20(5) : 328-339

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