Dear Authors,
If you believe that your paper was mistakenly rejected by other leading journals and you do not agree with final decision, the editors of Reports of Practical Oncology and Radiotherapy offer new fast track review. You may submit your manuscript to Reports of Practical Oncology and Radiotherapy together with all prior peer-reviews obtained from the other journal and your rebuttal letter. We guarantee review based decision within 72 hours from the time we will receive your manuscript.

Fast track submission process: Please submit the manuscript with all reviews and rebuttal letter by email to Dr. Michal Masternak ( for fast review processing. To assure immediate attention the email title must to include: RPOR-fast track- Last Name First Name (of corresponding author).

Volume 16, Number 6, 2011

Hyperfractionated high-dose rate brachytherapy in the treatment of oral tongue cancer

Lubos Tucek, Jiri Petera, Igor Sirák, Milan Vosmik, Helena Dolezalová,
Simona Brokesová, Miroslav Hodek, Linda Kasaová, Petr Paluska


Background: Low-dose rate brachytherapy is a well established treatment modality of oral
cancer. Data about high-dose rate (HDR) brachytherapy are still sparse with various fractionation
schedules and heterogeneous results.
Aim: The aim of our retrospective study was to evaluate the results of HDR brachytherapy
with doses of 3Gy twice daily.
Patients and methods: Twenty patients with squamous cell tongue cancer were treated in the
years 2001–2009 by exclusive HDR BT 18×3Gy twice daily. The plastic tube technique was
used. Median follow up was 47 months (7.8–118) since brachytherapy.
Results: The local and locoregional control was 85% and 68%, respectively. Bone necrosis
developed in one case treated without mandibular shielding and soft tissue necrosis in 2
Conclusion: It can be concluded that HDR brachytherapy with 18×3Gy twice daily is safe
with promising local control. The risk of nodal recurrences is substantial.

Signature: Rep Pract Oncol Radiother, 2011; 16(6) : 243-247

« back


Indexed in: EMBASE®, the Excerpta Medica database, the Elsevier BIOBASE (Current Awareness in Biological Sciences) and in the Index Copernicus.