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Volume 15, Number 5, 2010

A dosimetric analysis of 6 MV versus 15 MV photon energy plans for intensity modulated radiation therapy (IMRT) for carcinoma of cervix

Atul Tyagi,  Sanjay S Supe,  Sandeep Kaushik, Man P Singh


Aim: The objective of this study was to compare intensity modulated radiotherapy (IMRT)plans generated by 6 MV and 15 MV photon energies for carcinoma of cervix (Ca Cx) with regards to dosimetric parameters of planning target volume (PTV) and organs at risk (OAR), homogeneity index (HI), conformity index at 98% level (CI 98%), integral dose to normal tissue (NTID) and total number of monitor units (MUs).
Material and Methods: A cohort of 16 patients was selected for this study. All patients were to receive a dose of 50 Gy in 25 fractions. IMRT plans were generated for both energies using same dose-volume constraints.
Results: Our results show a comparable coverage of planning target volume (PTV) for both energies. Volume of PTV receiving a prescription dose is 97.8±0.5% and 98.8±0.4% for the 6 MV and the 15 MV plans. Volume of PTV receiving a dose of 107% is 4.4±7.8% and 16.1±22.2%. Bladder and rectum mean doses for the 6 MV and the 15 MV photon plans were 39.8±3.0 Gy and 40.0±3.2 Gy and 35.8±3.1 Gy and 36.0±3.1 Gy, respectively. The Homogeneity Index (HI) for both energies was 1.04. The Conformity Indices at 98% isodose (CI 98%) were 1.3±0.1 and 1.4±0.1 for the 6 MV and the 15 MV photon plans, respectively.
Conclusion: We conclude that a 6 MV photon is a good choice for Ca Cx IMRT as it produces a highly conformal, homogeneous plan with superior target coverage and better OAR sparing.

Signature: Rep Pract Oncol Radiother, 2010; 15(5) : 125-131

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